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Recommendations and Appraisals

Central nervous system

On this page you will find our appraisal documents and recommendations sorted by BNF chapter.

Where a decision is >24 months old; these are highlighted in red. If you are a clinician working within the
NTAG region and would like to prioritise an old decision for re-review please contact the professional secretary
on rdtc.rxsupp@nuth.nhs.uk


 

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Title

Documents

Decision

Date

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Agomelatine (Valdoxan®) for depression (NETAG)

Recommendation

Appraisal

Recommended for the treatment
of depression only following an adequate trial of at least three alternative antidepressant drugs at maximally tolerated doses

13/07/2010

  

Aripiprazole long acting injection (Abilify Maintena®) for schizophrenia

Recommendation

North of England Guidance

Appraisal

Recommended as per the North
of England Guidance

09/04/2015

 New
22 Mar 2019

Doxylamine/Pyridoxine (Xonvea®) for
nausea & vomiting in pregnancy

Recommendation

on hold

Not currently recommended pending further national guidance

26/02/2019

Erenumab and galcanezumab for prophylaxis of migraine

Recommendation

Appraisal

Not recommended

20/11/2018

e-Voke® electronic cigarette for smoking cessation

Recommendation

Appraisal

Not recommended

05/04/2016

 Liraglutide (Saxenda®) for Obesity in adults

Recommendation

Not recommended

05/09/2017

   

Lurasidone (Latuda®) for the treatment of schizophrenia in adults

Recommendation

Appraisal

Not recommended

09/04/2015

Lycra Garments for the management of cerebral palsy and other neurological or musculoskeletal conditions

Recommendation

Appraisal

Not recommended

04/09/2018

Novel fentanyl products (Abstral®, Effentora® Instanyl® and PecFent®): Updated appraisal for breakthrough pain associated with cancer (NETAG)

Recommendation

Appraisal

Not recommended

12/07/2011

Paliperidone long-acting monthly(Xepilon®)  and three monthly (Trevicta®) injection for schizophrenia

Recommendation

North of England Guidance

Appraisal

Recommended as per the North
of England Guidance

05/09/2017

Perampanel (Fycompa®) for Partial-onset (focal) epilepsy (NETAG)

Recommendation

Appraisal

Recommended only when other treatment options recommended by NICE have been tried or fully considered

13/11/2012

 

Pitolisant (Wakix®) for the treatment of narcolepsy with or without cataplexy in adults

Recommendation

Appraisal

Recommended as per the regionally agreed guidance

05/11/2018

Appeal Appraisal

Pitolisant (Wakix®) Treatment Pathway

 

Qutenza® (capsaicin patch) for neuropathic pain (updated)

Recommendation

Appraisal

Recommended as a fourth line agent in line with treatment pathway

06/06/2017

Qutenza® Treatment
Pathway

 

Sativex® for the treatment of non-MS pain

Recommendation

Appraisal

Not recommended

25/11/2014

Sodium oxybate(Xyrem®) for Narcolepsy with Cataplexy in adult patients (updated)

Recommendation

Appraisal

Recommended for continuation of treatment only, if benefited as a child.

06/06/2017

Transcutaneous vagus nerve stimulation for treatment of cluster headache and migraine

Recommendation

Appraisal

Not recommended

04/09/2018

 

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